CaPO4Sim: A Virtual Patient Simulator in the Context of Calcium and Phosphate Homeostasis

Explore calcium (Ca) and phosphate (Pi) homeostasis with two novel 'Shiny' apps, building upon on a previously published mathematical model written in C, to ensure efficient computations. The underlying model is accessible here <>. The first application explores the fundamentals of Ca-Pi homeostasis, while the second provides interactive case studies for in-depth exploration of the topic, thereby seeking to foster student engagement and an integrative understanding of Ca-Pi regulation. These applications are hosted at <>.

Version: 0.2.0
Imports: shiny, htmltools, shinyjs, shinyWidgets, shinydashboard, shinydashboardPlus, shinyjqui, plotly, rintrojs, shinycssloaders, visNetwork, purrr, DT, magrittr, utils
Published: 2021-03-21
Author: David Granjon [aut, cre, cph], Diane de Zélicourt [cph], Vartan Kurtcuoglu [cph], Olivier Bonny [cph], François Verrey [cph], University of Lausanne [fnd], University of Zurich [fnd], Kidney NCCR.CH [fnd], The Interface Group [cph] (Hosting Group), RinteRface [cph] (R/HTML Templates)
Maintainer: David Granjon <dgranjon at>
License: GPL-3
NeedsCompilation: no
Materials: README NEWS
CRAN checks: CaPO4Sim results


Reference manual: CaPO4Sim.pdf
Package source: CaPO4Sim_0.2.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): CaPO4Sim_0.2.0.tgz, r-release (x86_64): CaPO4Sim_0.2.0.tgz, r-oldrel: CaPO4Sim_0.2.0.tgz
Old sources: CaPO4Sim archive


Please use the canonical form to link to this page.